A study on the effects of Botox in treatment of chronic migraine, which was conducted by neurologists Associate Professor Elif Ilgaz Aydınlar, Associate Professor Pınar Yalınay Dikmen and Professor Ayşe Sağduyu Kocaman, was published in The Journal of Headache and Pain, one of the most globally well-known science journals on headache.

The study indicates that Botox injections constitute a very effective method of treatment on patients whose chronic migraine does not respond to other current treatment techniques. Chronic migraine is a condition which turns life into a nightmare for those suffering from it due to long-lasting and severe periods of headache. The currently applied treatments and the measures patients take against the condition by changing their daily habits are helpful in decreasing migraine attacks but while migraines can be kept under control through treatment, some patients simply do not respond to it. Until a few years ago, chronic migraine patients who could not be treated had to cope with the adverse psychological effects that were brought on by having to live with severe pain and exposure to the risks of continuous and excessive painkiller use. These patients, who had no choice but to endure their condition, now have a different treatment option available to them. This new and effective method of treatment, which received approval in the United States of America and England in 2010 and Turkey in 2011 after a series of studies on the subject, is Botox.

A study published in a world-renowned science journal

Botox, which is well-known for its use in the field of plastic surgery, is now also a treatment method for chronic migraine patients whose condition does not respond to oral drug therapy or changes in the lifestyle. A group of Turkish neurologists has recently contributed to scientific literature an important study on the efficiency of the method. The scientific article on the results of Botox treatment for chronic migraine, prepared by Associate Professor Elif Ilgaz Aydınlar, Associate Professor Pınar Yalınay Dikmen and Professor Ayşe Sağduyu Kocaman, who are neurologists at the Migraine Treatment Center of Acıbadem Maslak Hospital and academicians at the Department of Neurology Acıbadem University School of Medicine, was accepted by the editorial board of The Journal of Headache and Pain, and published in the February edition of the journal, which is one of the globally recognized publications on headache. The article, entitled ‘Onabotulinumtoxin A effectiveness on chronic migraine, negative emotional states and sleep quality: a single-center prospective cohort study’, indicated that Botox treatment reduced the severity and frequency of chronic migraine attacks significantly, as well as ensuring a considerable improvement in restoring migraine patients’ life quality and sleep patterns in cases where these were adversely affected by migraines.

“Very effective in treatment of chronic migraine”

Professor Ayşe Sağduyu Kocaman, one of the neurologists that conducted the study, stated that they have administered Botox injections to a large number of chronic migraine patients so far and said, “We recorded the experiences of these patients after each injection procedure and the data acquired from these records showed that the Botox method was very effective on chronic migraine”.
Neurologist/Associate Professor Elif Ilgaz Aydınlar, on the other hand, pointed out that their findings on migraine treatment were similar to those of their colleagues abroad and said, “The fact that our study on patients, conducted on a basis of long years of experience gained as a team, was accepted by the editorial board of The Journal of Headache and Pain and published in the journal makes us very proud”.
Neurologist/Associate Professor Pınar Yalınay Dikmen noted that Botox treatment starts to take effect in 10 days and that while the injections are administered once every three months during the first year due to the fact that the effects of the treatment are temporary, the injection intervals for the following years are determined according to the patients themselves.

Scientifically-proven effectiveness

The efficiency of Botox in treatment of chronic migraine was proven on a scientific basis as well. A series of scientific studies in the United States of America, which was entitled PREEMPT (Phase III Research Evaluating Migraine Prophylaxis Therapy), confirmed that the Botox method, which is commonly used for cosmetic purposes, is an effective solution in reducing the frequency and severity of chronic migraine attacks. The findings of these studies indicated that the Botox treatment was helpful in three thirds of the patients that received it. Following the emergence of this evidence, use of Botox injections for treatment of chronic migraine was approved in the United States of America and England in 2010 and Turkey in 2011.