Gamma Knife Icon

Gamma Knife Icon 2017-08-17T18:07:33+00:00


Gamma Knife PERFEXION for the Treatment of Brain Tumors Gamma Knife is superior to other techniques because:

It is more precise
Its technological features give it a precision of 0.3 mm.

It is more effective
Its efficacy has been proven through thousands of published scientific articles.

Scientific studies confirm that it obtains the best result without harming the patient.
Almost 3,000 medical journal articles have been published about Gamma Knife to date.

It is used in a large number of centers.
Gamma Knife is currently being used in about 300 centers around the world.

It has proven itself since 1968.
It is a radiosurgical technique that has been widely used for a long time.

What is Gamma Knife?
Gamma Knife, a radiosurgery technique, was first used in 1968. In the beginning, it was employed in very few centers around the world, but as its therapeutic benefits were confirmed, its sphere of use widened. Today, Gamma Knife is being used in about 300 centers around the world. According to statistics from 2012, approximately 600,000 patients with a variety of brain diseases have been treated with Gamma Knife. There is no other device in this field that can approach the precision of Gamma Knife and has helped this many people.

Other techniques report their efficacy by comparing themselves with Gamma Knife. Gamma Knife is viewed as the gold standard of radiosurgery.



The advanced technology Gamma Knife procedure makes it possible to treat brain tumors in a bloodless and painless fashion without open surgery so that the patient can return home the same day.
The term radiosurgery was introduced to the world of medicine by the Swiss brain surgeon Lars Leksell and refers to the process of directing numerous low-energy radioactive beams that do not damage brain tissue to the diseased area in the skull and alter the tissue by focusing on the diseased spot and releasing a strong dose of radiation only at this spot.

Gamma Knife Perfexion, the new state-of-the-art model from Gamma Knife, which is characterized as the gold standard in Radiosurgery, shortens the treatment process for brain tumors painlessly and without open surgery, offering the patient convenience and comfort. Its advanced computer program helps specialists in treatment planning.

How is it administered?
The Gamma Knife procedure basically involves identifying the diseased area in the skull which is stabilized with a stereotactic frame and directing gamma rays from 192 cobalt sources at this area. Low-energy beams of radiation from multiple sources deliver a strong dose of radiation to the points where radiation is aimed without damaging the healthy portion of the brain.

Which diseases is it used for?
Gamma Knife is used on AVM (congenital arteriovenous malformation in the brain), brain tumors and functional diseases. In order to use Gamma Knife, the tumor that will be treated must generally be smaller than 3.5 cm in diameter. Gamma Knife eliminates the need for anesthesia and intensive care and takes only a few hours, providing patients with a treatment option that does not involve surgery. Most patients are able to return to their normal lives the day after treatment.

Why is Gamma Knife preferred?
Today, people want to resolve their health problems with simpler procedures and extensive medical research is being conducted to achieve this. Gamma Knife radiosurgery meets this need because it is a technique that does not require the opening of the skull.

How Does Gamma Knife Work?
Stereotactic radiosurgery affects tissue like other radiotherapy techniques. With Gamma Knife the tumor or diseased tissue is not removed. Instead, the DNA of the cells is impaired, and as a result the tumor cells lose their normal functions and die because they are unable to divide and receive nourishment. The rate of tumor shrinkage is approximately equivalent to the rate of growth. In patients who have congenital abnormal tangle of blood vessels, also known as AVM, Gamma Knife causes the blood vessel walls to thicken and eventually clog up. The goal in treatment is to stop the growth of the tumor. If the tumor does not grow after treatment, this shows that the treatment was successful. Generally, the tumors shrink over time. However, the reduction in size may take years in benign tumors and months in malignant tumors and cases of metastasis. The obliteration of the AVM tangle of blood vessels occurs over a period of time, generally between 2-3 years.

The advantages of Gamma Knife treatment
It can eliminate the need for open surgery on many brain tumors
There few adverse effects following the procedure

Symptoms / Diagnosis

Return to normal life
It does not require general anesthesia
The patient can return to their home the day the treatment is performed
There is no recovery period
There is no incision on the scalp or head
Hair does not have to be cut and does not fall out
Tremendous benefit with little discomfort
Ability to return to work quickly
Less expensive than some surgical procedures
Healthy brain tissue is exposed to very little radiation

Advantages of Gamma Knife compared to surgery

Symptoms / Diagnosis

Open Surgery

1-4 days of Intensive Care
4-10 day hospital stay
4-6 week recovery period
Return to normal life

Areas in which Gamma Knife Radiosurgery is used
Gamma Knife has been used around the world since 1968 on an increasingly large number of patients with various indications. Gamma Knife is described as the “gold standard” in stereotactic radiosurgery. By 2012, almost 600,000 patients had been treated with it around the world. Gamma Knife radiosurgery is used at the ACIBADEM Healthcare Group Kozyatağı Hospital for the following indications.

Patients with blood vessel conditions
Arteriovenous malformation (AVM – congenital tangle of blood vessels in the brain)

Patients with benign tumors
Vestibular schwannoma (tumor on the hearing and balance nerve)
Pituitary tumor
Trigeminal schwannoma
Tumors of the pineal region
Glomus jugulare tumor

Patients with malignant tumors
Uveal melanoma
Certain glial tumors
Nasopharyngeal carcinoma

Patients with movement disorders
Tremors associated with Parkinson’s disease
Essential tremors

Patients with functional disease
Trigeminal neuralgia

Hard-to-reach tumors located deep in the brain

Patients unable to tolerate surgical procedures for reasons such as age, medical condition and general health status

Patients who refuse open surgery